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1

Determination of the c-MYC DNA-Binding Site

Thanos D. Halazonetis and Amany N. Kandil

Journal:

Proceedings of the National Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 1.24 MB

english, 1991

2

Familial holoprosencephaly associated with a translocation breakpoint at chromosomal position 7q36

Androniki G. Hatziioannou, Celeste M. Krauss, Michael B. Lewis, Thanos D. Halazonetis

Journal:

American Journal of Medical Genetics Part A

Year:

1991

Language:

english

File:

PDF, 604 KB

english, 1991

3

Chfr defines a mitotic stress checkpoint that delays entry into metaphase

Scolnick, Daniel M., Halazonetis, Thanos D.

Journal:

Year:

2000

Language:

english

File:

PDF, 257 KB

english, 2000

4

10.1038/542

Waterman, Matthew J. F., Stavridi, Elena S., Waterman, Jennifer L. F., Halazonetis, Thanos D.

Journal:

Nature Genetics

Year:

1998

Language:

english

File:

PDF, 258 KB

english, 1998

5

10.1038/5472

Waterman, Matthew J. F., Stavridi, Elena S., Waterman, Jennifer L. F., Halazonetis, Thanos D.

Journal:

Nature Medicine

Year:

1999

Language:

english

File:

PDF, 53 KB

english, 1999

6

Emerging common themes in regulation of PIKKs and PI3Ks

Lempiäinen, Harri, Halazonetis, Thanos D

Journal:

The EMBO Journal

Year:

2009

Language:

english

File:

PDF, 582 KB

english, 2009

7

TopBP1 functions with 53BP1 in the G1 DNA damage checkpoint

Cescutti, Rachele, Negrini, Simona, Kohzaki, Masaoki, Halazonetis, Thanos D

Journal:

The EMBO Journal

Year:

2010

Language:

english

File:

PDF, 1.82 MB

english, 2010

8

An induced fit mechanism regulates p53 DNA binding kinetics to confer sequence specificity

Petty, Tom J, Emamzadah, Soheila, Costantino, Lorenzo, Petkova, Irina, Stavridi, Elena S, Saven, Jeffery G, Vauthey, Eric, Halazonetis, Thanos D

Journal:

The EMBO Journal

Year:

2011

Language:

english

File:

PDF, 1.42 MB

english, 2011

9

Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks

Huyen, Yentram, Zgheib, Omar, DiTullio Jr, Richard A., Gorgoulis, Vassilis G., Zacharatos, Panayotis, Petty, Tom J., Sheston, Emily A., Mellert, Hestia S., Stavridi, Elena S., Halazonetis, Thanos D.

Journal:

Year:

2004

Language:

english

File:

PDF, 548 KB

english, 2004

10

Nbs1 moving up in the world

Stavridi, Elena S., Halazonetis, Thanos D.

Journal:

Nature Cell Biology

Year:

2005

Language:

english

File:

PDF, 165 KB

english, 2005

11

Chk2 leaves the PML depot

Venere, Monica, Mochan, Tamara A., Halazonetis, Thanos D.

Journal:

Nature Cell Biology

Year:

2002

Language:

english

File:

PDF, 212 KB

english, 2002

12

53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer

DiTullio, Richard A., Mochan, Tamara A., Venere, Monica, Bartkova, Jirina, Sehested, Maxwell, Bartek, Jiri, Halazonetis, Thanos D.

Journal:

Nature Cell Biology

Year:

2002

Language:

english

File:

PDF, 849 KB

english, 2002

13

Structure–based rescue of common tumor–derived p53 mutants

Wieczorek, Ania M., Waterman, Jennifer L.F., Waterman, Matthew J.F., Halazonetis, Thanos D.

Journal:

Nature Medicine

Year:

1996

File:

PDF, 627 KB

1996

14

Genomic instability — an evolving hallmark of cancer

Negrini, Simona, Gorgoulis, Vassilis G., Halazonetis, Thanos D.

Journal:

Nature Reviews Molecular Cell Biology

Year:

2010

Language:

english

File:

PDF, 495 KB

english, 2010

15

Defective apoptosis and B-cell lymphomas in mice with p53 point mutation at Ser 23

MacPherson, David, Kim, Jungho, Kim, Teresa, Rhee, Byung Kirl, van Oostrom, Conny Th M, DiTullio, Richard A, Venere, Monica, Halazonetis, Thanos D, Bronson, Roderick, de Vries, Annemieke

Journal:

The EMBO Journal

Year:

2004

Language:

english

File:

PDF, 476 KB

english, 2004

16

Two tandem and independent sub-activation domains in the amino terminus of p53 require the adaptor complex for activity

Candau, Reyes, Scolnick, Daniel M, Darpino, Paula, Ying, Carol Y, Halazonetis, Thanos D, Berger, Shelley L

Journal:

Year:

1997

Language:

english

File:

PDF, 1.02 MB

english, 1997

17

A serine 37 mutation associated with two missense mutations at highly conserved regions of p53 affect pro-apoptotic genes expression in a T-lymphoblastoid drug resistant cell line

Cinti, Caterina, Claudio, Pier Paolo, De Luca, Antonio, Cuccurese, Monica, Howard, Candace M, D'Esposito, Maurizio, Paggi, Marco G, La Sala, Dario, Azzoni, Livio, Halazonetis, Thanos D

Journal:

Year:

2000

Language:

english

File:

PDF, 412 KB

english, 2000

18

The Chfr mitotic checkpoint protein functions with Ubc13-Mms2 to form Lys63-linked polyubiquitin chains

Bothos, John, Summers, Matthew K, Venere, Monica, Scolnick, Daniel M, Halazonetis, Thanos D

Journal:

Year:

2003

Language:

english

File:

PDF, 252 KB

english, 2003

19

The CHFR mitotic checkpoint protein delays cell cycle progression by excluding Cyclin B1 from the nucleus

Summers, Matthew K, Bothos, John, Halazonetis, Thanos D

Journal:

Year:

2005

Language:

english

File:

PDF, 258 KB

english, 2005

20

Change in oligomerization specificity of the p53 tetramerization domain by hydrophobic amino acid substitutions

Elena S. Stavridi, Loretta C. Caruso, Nabil H. Chehab, Thanos D. Halazonetis

Journal:

Protein Science

Year:

1999

Language:

english

File:

PDF, 530 KB

english, 1999

21

Involvement of a p53-Dependent Pathway in Rubella Virus-Induced Apoptosis

Klara Megyeri, Klara Berencsi, Thanos D. Halazonetis, George C. Prendergast, Giorgia Gri, Stanley A. Plotkin, Giovanni Rovera, Eva Gönczöl

Journal:

Year:

1999

Language:

english

File:

PDF, 456 KB

english, 1999

22

Oncogene-induced senescence: the bright and dark side of the response

Vassilis G Gorgoulis, Thanos D Halazonetis

Journal:

Current Opinion in Cell Biology

Year:

2010

Language:

english

File:

PDF, 435 KB

english, 2010

23

Structural Differences in the DNA Binding Domains of Human p53 and Its C. elegans Ortholog Cep-1

Yentram Huyen, Philip D Jeffrey, W.Brent Derry, Joel H Rothman, Nikola P Pavletich, Elena S Stavridi, Thanos D Halazonetis

Journal:

Year:

2004

Language:

english

File:

PDF, 522 KB

english, 2004

24

Many faces of ATM: Eighth International Workshop on Ataxia-Telangiectasia

Thanos D. Halazonetis, Yosef Shiloh

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Year:

1999

Language:

english

File:

PDF, 176 KB

english, 1999

25

Crystal Structure of the FHA Domain of the Chfr Mitotic Checkpoint Protein and Its Complex with Tungstate

Elena S. Stavridi, Yentram Huyen, Ivy R. Loreto, Daniel M. Scolnick, Thanos D. Halazonetis, Nikola P. Pavletich, Philip D. Jeffrey

Journal:

Year:

2002

Language:

english

File:

PDF, 590 KB

english, 2002

26

Constitutively active DNA damage checkpoint pathways as the driving force for the high frequency of p53 mutations in human cancer

Thanos D. Halazonetis

Journal:

Year:

2004

Language:

english

File:

PDF, 94 KB

english, 2004

27

53BP1, an activator of ATM in response to DNA damage

Tamara A. Mochan, Monica Venere, Richard A. DiTullio Jr., Thanos D. Halazonetis

Journal:

Year:

2004

Language:

english

File:

PDF, 279 KB

english, 2004

28

Cellular responses to DNA damage: Current state of the field and review of the 52nd Benzon Symposium

Jiri Lukas, Vilhelm A. Bohr, Thanos D. Halazonetis

Journal:

Year:

2006

Language:

english

File:

PDF, 230 KB

english, 2006

29

SCFβTrCP-Mediated Degradation of Claspin Regulates Recovery from the DNA Replication Checkpoint Response

Angelo Peschiaroli, N. Valerio Dorrello, Daniele Guardavaccaro, Monica Venere, Thanos Halazonetis, Nicholas E. Sherman, Michele Pagano

Journal:

Year:

2006

Language:

english

File:

PDF, 687 KB

english, 2006

30

DNA Damage Signaling Recruits the RNA Polymerase II Binding Protein Che-1 to the p53 Promoter

Thanos D. Halazonetis, Jiri Bartek

Journal:

Year:

2006

Language:

english

File:

PDF, 144 KB

english, 2006

31

Alterations of the p16-pRb Pathway and the Chromosome Locus 9p21–22 in Non-Small-Cell Lung Carcinomas: Relationship with p53 and MDM2 Protein Expression

Vassilis G. Gorgoulis, Panayotis Zacharatos, Athanassios Kotsinas, Triantofillos Liloglou, Aspasia Kyroudi, Marinos Veslemes, Antonios Rassidakis, Thanos D. Halazonetis, John K. Field, Christos Kittas

Journal:

The American Journal of Pathology

Year:

1998

Language:

english

File:

PDF, 1.31 MB

english, 1998

32

Acetylation of p53 Activates Transcription through Recruitment of Coactivators/Histone Acetyltransferases

Nickolai A. Barlev, Lin Liu, Nabil H. Chehab, Kyle Mansfield, Kimberly G. Harris, Thanos D. Halazonetis, Shelley L. Berger

Journal:

Year:

2001

Language:

english

File:

PDF, 529 KB

english, 2001

33

ATM signaling and 53BP1

Omar Zgheib, Yentram Huyen, Richard A. DiTullio Jr, Andrew Snyder, Monica Venere, Elena S. Stavridi, Thanos D. Halazonetis

Journal:

Radiotherapy and Oncology

Year:

2005

Language:

english

File:

PDF, 147 KB

english, 2005

34

Studies of genomic copy number changes in human cancers reveal signatures of DNA replication stress

Aygül Dereli-Öz, Gwennaelle Versini, Thanos D. Halazonetis

Journal:

Molecular Oncology

Year:

2011

Language:

english

File:

PDF, 336 KB

english, 2011

35

c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities

Halazonetis, Thanos D., Georgopoulos, Katia, Greenberg, Michael E., Leder, Philip

Journal:

Year:

1988

Language:

english

File:

PDF, 2.19 MB

english, 1988

36

Ultraviolet-B-mediated induction of protein–protein interactions in mammalian cells

Crefcoeur, Remco P., Yin, Ruohe, Ulm, Roman, Halazonetis, Thanos D.

Journal:

Nature Communications

Year:

2013

Language:

english

File:

PDF, 795 KB

english, 2013

37

Conservative DNA Replication

Halazonetis, Thanos D.

Journal:

Nature Reviews Molecular Cell Biology

Year:

2014

Language:

english

File:

PDF, 589 KB

english, 2014

38

Reversal of the DNA-Binding-Induced Loop L1 Conformational Switch in an Engineered Human p53 Protein

Emamzadah, Soheila, Tropia, Laurence, Vincenti, Ilena, Falquet, Benoît, Halazonetis, Thanos D.

Journal:

Journal of Molecular Biology

Year:

2014

Language:

english

File:

PDF, 1.09 MB

english, 2014

39

Evolutionarily Conserved Regions of the Human c-myc Protein Can Be Uncoupled from Transforming Activity

Jacob Sarid, Thanos D. Halazonetis, William Murphy and Philip Leder

Journal:

Proceedings of the National Academy of Sciences

Year:

1987

Language:

english

File:

PDF, 592 KB

english, 1987

40

Identification of an Additional Negative Regulatory Region for p53 Sequence-Specific DNA Binding

Beate F. Muller-Tiemann, Thanos D. Halazonetis and James J. Elting

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1.59 MB

english, 1998

41

Microcollimator for Micrometer-Wide Stripe Irradiation of Cells Using 20–30 keV X Rays

Pataky, Kristopher, Villanueva, Guillermo, Liani, Andre, Zgheib, Omar, Jenkins, Nathan, Halazonetis, Demetrios J., Halazonetis, Thanos D., Brugger, Juergen

Journal:

Radiation Research

Year:

2009

Language:

english

File:

PDF, 347 KB

english, 2009

42

Phosphorylation of Ser-20 Mediates Stabilization of Human p53 in Response to DNA Damage

Nabil H. Chehab, Asra Malikzay, Elena S. Stavridi and Thanos D. Halazonetis

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.29 MB

english, 1999

43

DNA Replication Stress as a Hallmark of Cancer

Macheret, Morgane, Halazonetis, Thanos D.

Journal:

Annual Review of Pathology Mechanisms of Disease

Year:

2015

Language:

english

File:

PDF, 1.10 MB

english, 2015

44

Ubiquitin-H2AX fusions render 53BP1 recruitment to DNA damage sites independent of RNF8 or RNF168

Kocyłowski, Maciej K, Rey, Alix J, Stewart, Grant S, Halazonetis, Thanos D

Journal:

Year:

2015

Language:

english

File:

PDF, 4.44 MB

english, 2015

45

Structural Basis of Transcriptional Gene Silencing Mediated by Arabidopsis MOM1

Nishimura, Taisuke, Molinard, Guillaume, Petty, Tom J., Broger, Larissa, Gabus, Caroline, Halazonetis, Thanos D., Thore, Stéphane, Paszkowski, Jerzy, Wierzbicki, Andrzej T.

Journal:

Year:

2012

Language:

english

File:

PDF, 823 KB

english, 2012

46

Pocket Formation 3 Years after Comprehensive Periodontal Therapy*

Halazonetis, Thanos D., Smulow, Jerome B., Donnenfeld, O. Walter, Mejias, Judith E.

Journal:

Journal of Periodontology

Year:

1985

Language:

english

File:

PDF, 4.82 MB

english, 1985

47

Microcollimator for Micrometer-Wide Stripe Irradiation of Cells Using 20-30 KeV X Rays

Kristopher Pataky, Guillermo Villanueva, Andre Liani, Omar Zgheib, Nathan Jenkins, Demetrios J. Halazonetis, Thanos D. Halazonetis and Juergen Brugger

Journal:

Radiation Research

Year:

2009

Language:

english

File:

PDF, 2.26 MB

english, 2009

48

SAHF, to senesce or not to senesce?

Kocylowski, Maciej K., Halazonetis, Thanos D.

Journal:

Year:

2011

Language:

english

File:

PDF, 861 KB

english, 2011

49

Functional Interaction between BLM Helicase and 53BP1 in a Chk1-Mediated Pathway during S-Phase Arrest

Sagar Sengupta, Ana I. Robles, Steven P. Linke, Natasha I. Sinogeeva, Ran Zhang, Remy Pedeux, Irene M. Ward, Arkady Celeste, André Nussenzweig, Junjie Chen, Thanos D. Halazonetis and Curtis C. Harris

Journal:

The Journal of Cell Biology

Year:

2004

Language:

english

File:

PDF, 3.82 MB

english, 2004

50

DNA polymerases ν and θ are required for efficient immunoglobulin V gene diversification in chicken

Masaoki Kohzaki, Kana Nishihara, Kouji Hirota, Eiichiro Sonoda, Michio Yoshimura, Shigeo Ekino, John E. Butler, Masami Watanabe, Thanos D. Halazonetis and Shunichi Takeda

Journal:

The Journal of Cell Biology

Year:

2010

Language:

english

File:

PDF, 2.51 MB

english, 2010

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